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Science is the answer.

Trichology: The 10 Most Frequently Asked Questions by Patients with Androgenetic Alopecia

If you are experiencing hair loss, these questions will be very useful to you.  

1. WHAT IS ALOPECIA AND WHAT CAUSES IT?  

Alopecia is a term used to describe hair density loss. It is a medical condition that can have multiple causes, ranging from hormonal imbalances and nutritional deficiencies to immune disorders, medications, internal diseases, and even certain types of cancer. That’s why obtaining a precise diagnosis of the type of alopecia is essential in order to select the most appropriate treatment.  

2. IS ALOPECIA HEREDITARY, OR ARE THERE OTHER FACTORS THAT CONTRIBUTE TO ITS DEVELOPMENT?  

Androgenetic alopecia is the most common cause of hair loss. It is influenced by genetic and hormonal factors and affects both men and women. However, there are over 100 other types of alopecia, including alopecia areata (with an immune origin), telogen effluvium (which can be caused by stress, iron deficiency, thyroid hormone imbalances, etc.), primary scarring alopecias (autoimmune origin), drug-induced alopecia, and alopecia secondary to systemic diseases, among others.  

3. WHY DOES OUR HAIR FALL OUT?  

There are more than 100 different types of alopecia, ranging from those caused by hormonal and genetic factors, such as androgenetic alopecia, to those with immune origins (alopecia areata) or nutritional deficiencies (telogen effluvium). Hair loss can also be triggered by medications or internal diseases. This is why it is so important to obtain a precise diagnosis in order to determine the best treatment.  

4. WHEN SHOULD WE BE CONCERNED AND CONSULT A DOCTOR?  

It is normal to lose between 50 and 100 hairs per day as part of a continuous renewal cycle called effluvium, which is more pronounced in seasons like autumn. You should be concerned and see a doctor if hair loss becomes excessive or leads to a noticeable decrease in hair density, making the scalp visible. At that point, identifying the cause and acting accordingly is crucial. The first step is obtaining an accurate diagnosis to select the most suitable treatment.  

5. IS NUTRICOSMETICS A GOOD ALLY TO PREVENT HAIR LOSS?  

In general, nutricosmetic products can improve the cosmetic appearance of hair, but they are not a treatment for any form of alopecia. Dermatologists sometimes use them as a supplement to medical treatment, but they should never be used as a replacement. Additionally, it is not advisable to take them indiscriminately in response to seasonal hair loss.  

6. WHAT ARE THE MOST EFFECTIVE TREATMENTS FOR ANDROGENETIC ALOPECIA?  

The most effective medical treatments for androgenetic alopecia include:  

a) Antiandrogenic Medications: These prevent the action of male hormones on the hair follicle. In men, finasteride and/or dutasteride are used, making them the most effective treatments for androgenetic alopecia alongside minoxidil. These drugs are safe and have a very low rate of side effects, but treatment must be maintained for many years. Visible results typically begin after six months. Women requiring treatment can also use certain antiandrogenic medications but must avoid pregnancy during treatment. Antiandrogens can be taken orally, and in recent years, topical administration or scalp injections have proven to be effective alternatives.  

b) Minoxidil: A topical product (available as a liquid, spray, or foam) that stimulates hair growth by thickening fine hairs. It must be applied daily to the scalp and is a highly effective and safe treatment for both men and women. Long-term use is required, and the most common side effect is mild scalp irritation in some patients.  

c) Other Medical Therapies: Recent advancements include “platelet-rich plasma (PRP) therapy”, in which a patient’s own plasma is injected into the scalp to stimulate hair growth, and “low-level laser therapy”. While these treatments may be helpful for some patients, they generally have a lower efficacy rate compared to the primary treatments mentioned above.  

d) Hair Transplantation with Micrografts: Surgical treatment for alopecia has significantly improved in recent years. The current technique, known as “hair-by-hair” micrografting, allows for completely natural results. It is performed under local anesthesia and is suitable for both men and women. Recovery takes about 4-5 days before returning to work, and the final cosmetic results are visible after one year.  

e) Stem Cell Therapy: Despite ongoing research in this field, stem cell treatment is still far from being available outside of clinical studies, as current results in human trials remain very limited.  

7. IS FINASTERIDE TREATMENT SAFE? DOES IT CAUSE IMPOTENCE?  

Finasteride, along with minoxidil, is the most effective treatment for male androgenetic alopecia. It is a highly effective and completely safe medication, although it has gained a somewhat negative reputation. As many doctors say, “the worst thing about finasteride is its package insert”, as the listed side effects can seem alarming. However, in reality, it has an excellent safety profile.  

8. CAN DUTASTERIDE BE USED TO TREAT ALOPECIA?  

Dutasteride is another “5-alpha reductase inhibitor”, similar to finasteride but with a key difference: while finasteride inhibits part of the enzyme, dutasteride inhibits it completely. Although it is currently only approved for “benign prostatic hyperplasia”, there is strong scientific evidence supporting its use for male androgenetic alopecia (especially in cases of frontal or diffuse hair loss) and female alopecia (as long as the woman does not plan to become pregnant during treatment or for six months afterward). Dutasteride is a very effective and safe medication, and according to scientific studies and clinical experience, its risk of side effects is similar to that of finasteride—less than 2%.  

9. WHAT DOES A HAIR TRANSPLANT INVOLVE?  

Hair transplantation is a minimally invasive surgical procedure that involves transferring hair from a donor area, typically the back of the scalp (where hair is resistant to alopecia), to the affected area. The procedure used is “follicular unit transplantation (FUT)”, which allows hair follicles to be moved from a dense area to a balding one, increasing hair density and achieving a “completely natural” result. This minimally invasive technique is suitable for both men and women, and patients can return to their social and work activities within a few days.  

10. IS THERE ANY PRODUCT THAT CAN RESTORE OR REGENERATE HAIR FOLLICLES?  Currently, the only medical treatments that have been scientifically proven to be effective for androgenetic alopecia are “minoxidil and antiandrogens”. Other modern treatments, such as “platelet-rich plasma therapy” and “scalp injections of antiandrogens”, may serve as complementary therapies. However, many products that claim to regenerate hair using plant-based compounds  lack scientific evidence and are not effective

If you are struggling with hair loss, these questions and answers may help you understand your condition and explore the best available treatments

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